Search Results - hsueh-chia chang

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Method and Apparatus for AC Electrospray
AC Electrospray Ionization: DC electrospray techniques are employed with a great deal of success for the formation of aerosols for various uses such as drug delivery and compound analysis. Researchers at the University of Notre Dame have uncovered the unique characteristics of operating an AC electrospray device. The AC spray produces encaps...
Published: 3/10/2015   |   Inventor(s): Hsueh-Chia Chang, Shau-Chun Wang, Leslie Yeo, Siddharth Maheshwari, Dmitri Lastochkin, Zachary Gagnon
Keywords(s):  
Category(s): Life sciences
Hypersensitive Molecule Sensing by Dynamic Assembly of Nanoparitcles in Conic Nanopores (DANCON)
A sensitive and low cost platform for nucleic acid, protein and chemical sensing utilizing functionalized nanoparticles within a nanopipette environment. Detection of particles or aggregates of particles can be conducted optically, electrically, or through plasmon based techniques.
Published: 5/24/2013   |   Inventor(s): Hsueh-Chia Chang, Shoupeng Liu, Satyajyoti Senapati, Yunshan Wang, Yu Yan
Keywords(s):  
Category(s): Life sciences
Rapid, Label-Free and High-Throughput Electrokinetic Membrane Biosensors with Surface-Charge Inversion Signature, Buffer Composition Control and Micro-Circulation Sensitivity Enhancement
A rapid and label-free biosensor for the detection of DNA, RNA and other molecular biomarkers at high throughput. This technology is based on how molecular docking can affect surface charge on a membrane and alter both local hydrodynamics and ion transport. This affect is can be measured sensitively and accurately.
Published: 11/28/2012   |   Inventor(s): Zdenek Slouka, Satyajyoti Senapati, Li-Jing Cheng, Hsueh-Chia Chang
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Category(s):  
Integrated DC Pump/Electrospray
Formulation and aeration of nanodroplets for use in analytical instrumentation and drug delivery
Published: 11/28/2012   |   Inventor(s): Hsueh-Chia Chang, Zilin Chen, Ping Wang
Keywords(s):  
Category(s): Microfluidic Devices
Method and Apparatus for AC Electrospray
AC Electrospray Ionization: DC electrospray techniques are employed with a great deal of success for the formation of aerosols for various uses such as drug delivery and compound analysis. Researchers at the University of Notre Dame have uncovered the unique characteristics of operating an AC electrospray device. The AC spray produces encaps...
Published: 11/28/2012   |   Inventor(s): Hsueh-Chia Chang, Shau-Chun Wang, Leslie Yeo, Siddharth Maheshwari, Dmitri Lastochkin, Zachary Gagnon
Keywords(s):  
Category(s): Microfluidic Devices
Capture and Release of Viruses through Amino-Functionalized Silica Particles
Background: A new virus capture/release strategy for the concentration of viral particles in water is reported. The method is an improvement to traditional approaches that rely exclusively upon electrostatic attractions between a charged substrate and charged viral particles, which can only be reversed under extremely acidic or alkaline conditions ...
Published: 11/28/2012   |   Inventor(s): Hsueh-Chia Chang, Zilin Chen
Keywords(s):  
Category(s): Life sciences
A Nanoslot DNA Sensor for Quantitative Real-Time PCR
A Nanoslot DNA Sensor for Quantitative Real-Time PCR. PCR amplification can now take place at the chip-scale. However, detection of amplicons is time consuming. This technology, however is based on the observation that a sensitive conductance change in the solution can be measured when small charged ions are converted into large DNA molecules.
Published: 11/28/2012   |   Inventor(s): Hsueh-Chia Chang, Peter Mushenheim, Gilad Yossifon, Sagnik Basuray, Satyajyoti Senapati
Keywords(s): Diagnostic
Category(s): Healthtech, Life sciences
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