Disease Driven Engineering of Multifunctional Nanoparticles and Method of Use

Description:

Engineered nanoparticles functionalized to target malignant cells such as those comprising multiple myeloma, lymphomas, and leukemia can be used in numerous cancer therapeutics.  These nanoparticles can also be used to increase the effectiveness of current market therapeutics against cancers which exhibit drug resistance.  The nanoparticles contain a cell penetrating peptide and a target specific peptide to facilitate drug entry.  The nanoparticle target diseased cells to reduce the toxic effect of a drug on healthy organs with longer circulation time.

 

Patent Information:
Category(s):
Therapeutic
For Information, Contact:
Karen Deak
Director
University of Notre Dame
574 631-6695
kdeak@nd.edu
Inventors:
Zihni (Basar) Bilgicer
Tanyel Kiziltepe Bilgicer
Jonathan Ashley
Jared Stefanick
Keywords:
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