MMPs that cross the blood-brain barrier


Matrix metalloproteinase play and important role in the pathology of many neurological diseases.  Disclosed as part of this invention are novel small molecule therapeutic candidates which are capable of crossing the blood-brain barrier.  These compounds may be effective treatments for chronic wounds, certain forms of cancer, traumatic brain injury, and neurological diseases.

Patent Information:
For Information, Contact:
Richard Cox
Director, Technology Commercialization
University of Notre Dame
(574) 631-5158
Mayland Chang
Shahriar Mobashery
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