Gelatinase Inhibitors and Prodrugs

Description:

Compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix metalloproteinase (MMPs) can be useful in the treatment of stroke and neurological disorders .  Providing a prodrug compound that metabolizes to an active MMP inhibitor in vivo.  MMP inhibition can be selective, thus non-mutagenic prodrug compounds and formulas can be developed.       

Patent Information:
Category(s):
Therapeutic
For Information, Contact:
Richard Cox
Director, Technology Commercialization
University of Notre Dame
(574) 631-5158
rcox4@nd.edu
Inventors:
Mayland Chang
Shahriar Mobashery
Mijoon Lee
Keywords:
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