Treatment for Diabetic Chronic Wounds

Description:

Matrix metalloproteinase (MMPs) is responsible for the turnover and degradation of the extracellular matrix, including collagen.  We have evidence that certain selective MMP inhibitors are effective in the treatment of chronic wounds.  We have evaluated three such inhibitors in a mouse model of diabetic wounds and have shown that the compounds are efficacious in speeding the healing process.

 

Patent Information:
Category(s):
Therapeutic
For Information, Contact:
Gaylene Anderson
Sr. Innovations Officer
University of Notre Dame
574-631-9692
andersg4@ccf.org
Inventors:
Shahriar Mobashery
Mark Suckow
Mayland Chang
Mijoon Lee
Keywords:
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