Non-Aqueous Electrophoretic Separation System for Bioanalysis and Pharaceutical Screening

Description:

This is a point-of-care separation system capable of in-vivo analysis of biomolecular samples.  The microfluidic platform utilizes a completely non-aqueous separation solvent, enabling the label-free detection of biomarkers.  Coupled with microdialysis sampling upstream, and portable mass spectrometry downstream, this device can be used to provide invaluable clinical information at the patient's bedside.

 

Applications:

Real-time monitoring of one or more biomarkers for tracking disease progression

Pharmaceutical quality control

Pharmaceutical target screening

 

Benefits:

Inexpensive (less that $1 in raw materials per test)

Results in minutes

Only nanoliters of sample and separation reagents consumed

Easily paired with MS, UV, UV-Vis absorption, electrochemical, or fluorescence detection

Patent Information:
Category(s):
Medical Diagnostics
For Information, Contact:
Arnaud Cottet
Technology Commercialization Manager
University of Notre Dame
(574) 631-9766
acottet@nd.edu
Inventors:
Paul Bohn
Larry Gibson
Keywords:
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