Capillary electrophoresis instrumentation and method for forensic analysis of sexual assault evidence

Description:

In order to address the national backlog in processing sexual assault kits, a purified sample of male DNA must be selectively retrieved from a gynecological swab. Effective elution of the sample from the swab and efficient separation of intact sperm cells from epithelial cells and other debris allow for a successful polymerase chain reaction (PCR) amplification and short tandem repeat (STR) analysis of the perpetrator DNA. An improved method to perform the cell separation boasts three major advantages over present technologies: small sample size allowing for multiple analysis of limited available evidence, rapid separation time compared to standard methods and single cell detection and collection. In this invention, sperm migrate in a confined band in less than 30 minutes. The sample is collected into individual wells on a well-plate. The isolated sample will then undergo PCR amplification and STR analysis for forensic identification.

Patent Information:
Category(s):
Biotechnology
Devices
For Information, Contact:
Tim Joyce
Technology Commercialization Manager
University of Notre Dame
(574) 631-3029
tjoyce2@nd.edu
Inventors:
Norman Dovichi
Sarah Lum
Bonnie Huge
Carlos Gartner
Keywords:
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