Diagnosis of inflammation from H&E staining images


Tissue samples are processed using hematoxylin and eosin (H&E) staining techniques in order to generate histology tissue images for inflammatory disease diagnosis.  Conventionally, H&E stained histology tissue images are manually analyzed by a trained pathologist, which can be tedious and time consuming.  A computer automated image analysis system has been developed to identify features of the subcellular structures, such as the nucleus and cytoplasm.  This permits easy identification and differentiation of immune cell types.  Accurate segmentation of the subcellular structures can help classify cell types.  Gland villi and immune cells are then output to the user for further clinical use.

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Identification of Inflammation in Tissue Images Utility United States 15/264,836 10,121,245 9/14/2016 11/6/2018 11/8/2036 Patent Issued
Life sciences
For Information, Contact:
Kunigunda Szentes
2 Stroke Manager
University of Notre Dame
Danny Chen
Rageshree (raga) Ramachandran
John Mackenzie
Jiazhuo Wang
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